Company talk by SomaScan

Proteomics and Beyond
Combining Protein- and Immuno-Profiling to reveal novel biological insights

Speaker: Thomas Bauer, Sr. Executive Terrtory Account Managere (Germany)

Biomarkers are measurable indicators of normal biological function or indicate pathogenic processes or specify biological changes . They are mostly used as diagnostic, prognostic, or predictive tool. Typically, Biomarkers today are related to the protein field where Slow Off-Rate Modified Aptamers (SOMAmer) can be used for Protein-Profiling, reliably detecting up to 11.000 Protein targets at the same time in minimal sample volume, highly specific, precise, and reproducible.

An additional valuable information is to gather information about the Immuno-Profile by multiplex detection of Antibodies, precisely Autoantibodies using fully expressed, correctly folded proteins (KREX). The humoral immune system surveys the body for danger and marks potentially harmful proteins with antibodies. This includes aberrantly expressed proteins that often appear in diseases like Cancer, Autoimmunity, Infectious disease, or Neurology but also play a key role in the Microchimerism context.