Thursday, 28.05.2026, Day 2
Time: 9:00 – 10:15
Recent developments in cell-free DNA-based diagnostics
Y. M. Dennis Lo
Department of Chemical Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
Cell-free DNA in bodily fluids such as plasma offers exciting diagnostics opportunities, such as for noninvasive prenatal testing, cancer liquid biopsy and transplantation monitoring. Recent understanding of the characteristics of cell-free DNA, such as its end characteristics (including end motifs and jagged ends) and the existence of long cell-free DNA (up to kilobases in length) has offered new research and diagnostic opportunities. In this lecture, I shall review some of these recent developments, hoping that it would also have implications to research into chimerism.